Develops RNA-activation and siRNA medicines. RAG-17 targets SOD1; its April 21, 2026 release reports Phase 1/2 and Phase 2 dosing, whereas its undated pipeline still says Phase 1.
Profile review: 2026-11-07 · Fields retain their individual source dates. Undisclosed values are not zero; early or historical events do not establish the latest financing. Awards and acquisitions are distinguished from equity rounds.
Disease tags match recorded text mentions and require program-level verification.
Founded in 2017; the company lists Suzhou headquarters, Rudong manufacturing and a Shanghai business office.
RNAa uses small activating RNA; saRNA here does not mean self-amplifying mRNA.
| Program / service | Target / indication | Representative stage | Evidence & scope |
|---|---|---|---|
| RAG-17 | SOD1 · SOD1-associated ALS | Phase 1/2；2026-04-21Company announcement称II期给药中 | Investigational human study |
Company-name matches are discovery leads; verify entity identity and transaction roles in the original source.
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Vir Biotechnology announced that Phase 3 ECLIPSE 1 results for elebsiran plus tobevibart in chronic hepatitis delta will be presented on November 8, with an investor discussion on November 9. Elebsiran is an HBV-targeting siRNA; tobevibart is an antibody. The release announces the forthcoming readout and expanded Phase 2 presentations but does not disclose the Phase 3 numerical results.
Nitto Denko Avecia and EnPlusOne signed an evaluation agreement for the ezRNA enzymatic synthesis platform. The phased program covers proof-of-concept studies, laboratory process evaluation, and technology transfer at Avecia facilities. The platform uses a water-based, template-free process. The agreement evaluates manufacturing feasibility; it does not announce a completed commercial manufacturing contract or a definitive platform license.
IDT and Aldevron launched PE Ultra prime-editor mRNA, chemically modified pegRNAs, and six ABE8e-based editor mRNAs with a parallel screening kit. The companies also described guide-design support and stocked quantities from 20 micrograms to 1 milligram. These are research-use products; the announcement does not establish clinical safety, efficacy, or approval.
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