Protein expression kinetics of mRNA, saRNA, and pDNA as individual or co-delivered payloads using a common lipid nanoparticle formulation
McMillan C; Hussain M; Punnabhum P; Varley AJ; Kong KYS; Rattray Z; Druschitz A; Perrie Y Journal of controlled release : official journal of the Controlled Release Society · DOI 10.1016/j.jconrel.2026.115418
Targeted Gastrointestinal Delivery of mRNA Lipid Nanoparticles Enables Systemic Vaccination and Glucagon-like Peptide-1 Metabolic Therapy
Abdulraouf M. Abbas; Ramy Ghanim; Sebastian Rudden; David Schultz; Bora Jang; Avraham Shakked; Hyejin Kim; James E. Dahlman; Alex Abramson ACS nano · DOI 10.1021/acsnano.5c18549
Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency
Yao Zhang; Jerry Leung; Judy Cheng; Arash Momeni; Albert Kamanzi; Ariadne Tuckmantel Bido; Suiyang Liao; Emma Kang; Colton Strong; Christian J. Kastrup; Sabrina Leslie; Miffy Hok Yan Cheng; Pieter R. Cullis Advanced Materials · DOI 10.1002/adma.75174
Lipid Nanoparticle Surface Engineering with Heparosan Polysaccharides Enhances mRNA Efficacy via Reduced Endosomal Retention
Yuxin He; Lin Wang; Abigael P. Williams; Trisha I. Valerio; Yuanhong Sun; James Bowman; Samantha D. Ricketts; Savannah Hammond; Aidan Sison; Jezan Alexandre; Zachary Niastor; Wei R. Chen; Dixy E. Green; Kar-Ming Fung; Paul L. DeAngelis; Stefan Wilhelm ACS nano · DOI 10.1021/acsnano.6c11865
Targeting tumor-associated macrophages using mRNA lipid nanoparticles for cytotoxic T lymphocyte-mediated cancer immunotherapy
Rui Chen; Letao Xu; Alexander H. Staudacher; Xing Wang; Ruoxuan Jia; John W. Finnie; Xiaoyan Wang; Dawn M. Whelan; Michael P. Brown; Chun-Xia Zhao Science advances · DOI 10.1126/sciadv.aed9568
Spray Freeze Drying for Solid Formulations of RNA Lipid Nanoparticles
Kinnari Santosh Arte; Rachana Sapkota; Chanakya D. Patil; Yijing Huang; Eric J. Munson; Sajal Patel; Nicole Payton; Rushit Lodaya; Qi Tony Zhou; Li Lily Qu AAPS PharmSciTech · DOI 10.1208/s12249-026-03516-1
