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Moderna reports initial mRNA-2808 T-cell engager results in multiple myeloma

Company / institutional announcement · Moderna / ACCESS Newswire

Source published: · Event / reporting date: 2026-11-04

Site published: 2026-11-05 · Updated: 2026-11-05

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What changed

Moderna reported initial Phase 1/2 MyEngage findings for mRNA-2808, which encodes three T-cell engagers. Four confirmed responses occurred among 11 response-evaluable patients. Twelve patients had received treatment; Grade 3 or higher treatment-related adverse events occurred in 41.7%. These small, uncontrolled findings are preliminary and do not establish comparative benefit.

Why it may matter

Analysis: The results offer early human evidence for multiplexed mRNA protein production; durability, dose optimization, and safety require further evaluation.

The interpretation above is analysis, not a conclusion attributed to the original source.

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Prepared through Biotech Assistant’s automated research workflow. Editorial standards and corrections

mRNA / LNP

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