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Oral-peptide reference: Haisco reports HSK47388 Phase 1 and enhancer-formulation findings

Company / institutional announcement · Haisco Pharmaceutical

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Site published: 2026-11-03 · Updated: 2026-11-03

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Findings and limitationsIndustry implicationsRelated developments

What changed

Haisco reported Phase 1 and formulation pharmacokinetic findings for oral IL-23 peptide HSK47388. Exposure with a 50 mg enhancer formulation was comparable to a 200 mg tablet without enhancer, and the company said psoriasis Phase 2 began in fourth-quarter 2025. Public materials identify an oral peptide but do not fully disclose cyclization; relative exposure is not absolute bioavailability.

Why it may matter

Informs enhancer-formulation comparisons while keeping cyclic structure and absolute bioavailability separate from the company’s reported relative exposure.

The interpretation above is analysis, not a conclusion attributed to the original source.

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Oral cyclic peptides

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