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COMPANY RESEARCH

Ionis Pharmaceuticals, Inc.

Ionis Pharmaceuticals is a United States company focused on medicines that target RNA to address serious diseases. Its research and marketed medicines draw on oligonucleotide technologies, including antisense approaches that can change production or processing of disease related proteins. Its therapeutic areas include neurological and cardiometabolic conditions, alongside selected rare diseases. Founded in 1989, Ionis is headquartered in Carlsbad, California, and has conducted public trading under the Nasdaq ticker IONS. Several medicines are developed independently and through partnerships.

Company at a glance

Corporate information

Company entity
Ionis Pharmaceuticals
Headquarters / principal office
Carlsbad, California, United States
Sources (1)
Founded
1989
Sources (1)
Ownership / capital status
Publicly tradedPublicly traded (NASDAQ: IONS; IPO in 1991)
Sources (1)
Official corporate reference
https://ionis.com/
Sources (1)
LinkedIn company page
LinkedIn ↗
Sources (1)

Profile review: 2026-11-04 · Fields retain their individual source dates. Undisclosed values are not zero; early or historical events do not establish the latest financing. Awards and acquisitions are distinguished from equity rounds.

Listed issuer and R&D focus

Ionis Pharmaceuticals is a United States company focused on medicines that target RNA to address serious diseases. Its research and marketed medicines draw on oligonucleotide technologies, including antisense approaches that can change production or processing of disease related proteins. Its therapeutic areas include neurological and cardiometabolic conditions, alongside selected rare diseases. Founded in 1989, Ionis is headquartered in Carlsbad, California, and has conducted public trading under the Nasdaq ticker IONS. Several medicines are developed independently and through partnerships.

Nasdaq: IONS

antisense oligonucleotides · RNA-targeted medicines

neurology · cardiometabolic · rare diseases

Last independently verified:

Disease tags match recorded text mentions and require program-level verification.

Technology, programs & evidence

Ionis describes a portfolio of RNA- and DNA-targeted medicines, with separate pipeline, medicines, clinical-trial, and scientific-publication resources. Product-specific mechanisms and development status should be checked against dated disclosures.

Business, technology & evidence

  • Ionis Pharmaceuticals is a United States company focused on medicines that target RNA to address serious diseases. Its research and marketed medicines draw on oligonucleotide technologies, including antisense approaches that can change production or processing of disease related proteins. Its therapeutic areas include neurological and cardiometabolic conditions, alongside selected rare diseases. Founded in 1989, Ionis is headquartered in Carlsbad, California, and has conducted public trading under the Nasdaq ticker IONS. Several medicines are developed independently and through partnerships.
  • SecuritiesNasdaq: IONS
Program / serviceTarget / indicationRepresentative stageEvidence & scope
ION717PRNP · Prion diseaseI/IIa期;公司资料Human/approved evidence; see original source for scope
obudanersen / ION582UBE3A-ATS · Angelman syndromePhase 3REVEAL;公司资料Human/approved evidence; see original source for scope

Related news & literature

Company-name matches are discovery leads; verify entity identity and transaction roles in the original source.

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Sources & open questions

  • Two representative programs added; not a complete pipeline. Later developments, registry status and other indications remain to be checked.
  1. Ionis Pharmaceuticals — official website ↗Ionis Pharmaceuticals · 2026-11-04 retrieval
  2. Ionis neurology pipeline: PrProfile and REVEAL ↗Ionis Pharmaceuticals · 2026-08-28
  3. Official issuer and R&D disclosure · Ionis Pharmaceuticals, Inc. ↗Ionis Pharmaceuticals, Inc. ·
  4. Official issuer and R&D disclosure · Ionis Pharmaceuticals, Inc. ↗Ionis Pharmaceuticals, Inc. ·
  5. Official issuer and R&D disclosure · Ionis Pharmaceuticals, Inc. ↗Ionis Pharmaceuticals, Inc. ·
  6. Official issuer and R&D disclosure · Ionis Pharmaceuticals, Inc. ↗Ionis Pharmaceuticals, Inc. ·
  7. Ionis investor FAQs ↗Ionis Pharmaceuticals · Accessed 2026-11-04; undated unless stated

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