COMPANY RESEARCH

HitGen

The company's interim report describes peptidomimetic macrocycle discovery, optimization, and oral applications. DEL and platform capabilities do not establish human oral evidence for proprietary candidates.

Company at a glance

Corporate information

Company entity
成都先导药物开发股份有限公司
Headquarters / principal office
Chengdu, Sichuan, ChinaCorporate website explicitly identifies headquarters; location follows the retrieved disclosure. ↗
Founded
2012 ↗
Ownership / capital status
Publicly tradedPublicly traded (Shanghai STAR Market) ↗
Official corporate reference
https://www.hitgen.com/ ↗
LinkedIn company page
LinkedIn ↗ ↗

Profile review: 2026-11-04 · Fields retain their individual source dates. Undisclosed values are not zero; early or historical events do not establish the latest financing. Awards and acquisitions are distinguished from equity rounds.

Public financial snapshot

Amounts retain their original currency and units. Consolidated group revenue is not standalone CRO/CDMO service revenue. Year-to-date periods are not standalone quarters.

PeriodCurrency / basisRevenueNet profitOperating cash flowReport
FY2025
2025-12-31
CNY
PRC Accounting Standards / consolidated
525,571,768.68109,505,443.81
Net income attributable to shareholders of the listed company
216,347,757.1Original ↗
2026Q3 (YTD)
2026-09-30
CNY
PRC Accounting Standards / consolidated
549,978,876.88139,415,069.57
Net income attributable to shareholders of the listed company
180,509,466.49Original ↗
FY2025 · Reporting notes
  • Consolidated group financials; not standalone CRO/CDMO segment revenue.
  • Source unit: CNY.
2026Q3 (YTD) · Reporting notes
  • The latest report covers January–September 2026 year to date, not the third quarter alone; unaudited quarterly report.
  • Consolidated group financials; not standalone CRO/CDMO segment revenue.
  • Source unit: CNY.

Disease tags match recorded text mentions and require program-level verification.

Technology, programs & evidence

The company's interim report describes peptidomimetic macrocycle discovery, optimization, and oral applications. DEL and platform capabilities do not establish human oral evidence for proprietary candidates.

Provides research services using DEL, FBDD/SBDD, and other small-molecule discovery platforms and emerging technologies, alongside proprietary discovery and translation.

Listed as SSE 688222; original 2025 annual and 2026Q3 (YTD) reports reviewed.

Program / serviceTarget / indicationRepresentative stageEvidence & scope
Cyclic peptide-like / DEL platform for oral applicationsNot disclosed · Not disclosed未披露Quantitative human results not confirmed in this review
DEL / FBDD / SBDD drug discoveryNot applicable (services/platform) · Drug research and manufacturing services for clientsServices / platformNot applicable: service capabilities are not clinical drug candidates; E4 does not rate service quality.

Related news & literature

Company-name matches are discovery leads; verify entity identity and transaction roles in the original source.

成都先导 / 巨潮资讯 CNinfo

HitGen reports nine-month revenue growth of 48.73%

HitGen reported consolidated revenue of RMB0.550 billion, up 48.73%, and attributable net income of RMB139.4 million for the nine months ended September 30, 2026. Attributable net income increased 50.11%. These are consolidated year-to-date figures rather than third-quarter-only results. The quarterly filing is unaudited and covers the year-to-date period.

Bioconjugate Chemistry

Synthesis of DNA-Encoded Bicyclic Peptides via Cysteine-Promoted Cyclization and Amide Condensation Reaction

HitGen researchers describe a method for synthesizing DNA-encoded bicyclic peptides using cysteine-promoted cyclization and amide condensation under mild conditions. The abstract reports compatibility with varied sequences and ring sizes. This is discovery-platform chemistry, not evidence that the resulting peptides have oral exposure, clinical efficacy, or validated manufacturing-scale performance.

Same-field reading (not company-specific)
Fresenius

Fresenius gains development options on up to 37 WuXi Biologics biosimilar candidates

Fresenius signed an exclusive development agreement with WuXi Biologics providing access to up to 37 biosimilar candidates over the next decade. Initial work is expected to focus on polatuzumab vedotin and teprotumumab biosimilars. Fresenius retains selection flexibility and commercialization economics; the candidate count is an option-based opportunity, not 37 approved products.

AJMC

Enlicitide reports address durability and baseline cardiovascular risk

Ahead of the AHA meeting, an original report reviewed enlicitide analyses across PREVENT cardiovascular risk groups and an open-label extension. LDL cholesterol reductions were broadly consistent across risk categories and persisted through Week 104. The extension selected participants who had tolerated and adhered to treatment and lacked a control group, limiting generalization of its long-term findings.

Aurinia / SEC

Aurinia reports $232.4 million in nine-month LUPKYNIS net product sales

Aurinia reported LUPKYNIS net product sales of $232.4 million for the nine months ended September 30, 2026, up 18%, including $79.4 million in the third quarter, up 12%. Total company revenue also includes licensing, collaboration, and royalty income. These are commercialization results for an approved oral cyclic peptide, rather than a new indication approval or clinical endpoint readout.

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Sources & open questions

  • Public information reviewed is insufficient to reconstruct the complete formulation, absolute bioavailability, variability, or food effects.
  • Financials are consolidated figures for the listed group. Revenue by service line, available capacity, and project fit require further verification at the segment and operating-entity levels.
  1. 先导 2026 半年报:类环肽与口服方向 ↗成都先导 · 巨潮原始公告 · 2026-08-27
  2. 成都先导药物开发股份有限公司2026年第三季度报告 ↗成都先导 · 2026-10-29
  3. 成都先导药物开发股份有限公司2025年年度报告 ↗成都先导 · 2026-04-29
  4. HitGen history ↗HitGen · Not stated
  5. HitGen company page ↗HitGen · Not stated
  6. DNA encoded library | HitGen — official page checked ↗HitGen · Undated page; retrieved 2026-11-04
  7. Official company contact / corporate location disclosure ↗HitGen · Checked 2026-11-04; source publication date retained where stated

Inclusion is not endorsement or partner qualification. Assess company claims, clinical evidence, and project-specific capabilities separately.

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