Cryo-EM–microcrystal electron diffraction structural elucidation of cefadroxil: nanocrystallographic and neurotherapeutic insights into a β-lactam antibiotic
Academic source · Journal of Applied Crystallography
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Site published: 2026-11-03 · Updated: 2026-11-03
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What the paper reports
The authors reported a cryo-MicroED structure of cefadroxil, characterizing its molecular geometry, stereochemistry, and intermolecular packing. The crystallographic model also supported complementary molecular-dynamics analysis. This is a structural case study of an established beta-lactam antibiotic; the accompanying computational work should not be interpreted as clinical evidence of a new neurotherapeutic benefit or a general performance guarantee.
Why this paper is included
A relevant antibiotic structure example, useful for evaluating what MicroED establishes experimentally and what remains an interpretation from downstream computational models.
The interpretation above is analysis, not a conclusion attributed to the original source.
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