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Hansoh presents Phase 1 HS-20118 data supporting exploration of weekly oral dosing

Company / institutional announcement · Hansoh Pharma

Source published: · Event / reporting date: 2026-05-14

Site published: 2026-11-03 · Updated: 2026-11-03

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Findings and limitationsIndustry implicationsRelated developments

What changed

Hansoh presented two randomized, double-blind, placebo-controlled Phase 1 studies of HS-20118 involving 129 treated participants, including healthy volunteers and 23 patients with psoriasis. The company reported sustained pharmacokinetic and pharmacodynamic activity and early skin-response signals supporting exploration of weekly oral dosing. Small patient cohorts and short treatment duration limit conclusions about comparative efficacy and long-term safety.

Why it may matter

Adds early human evidence for oral IL-23R peptides; weekly dosing and durable benefit require larger controlled studies.

The interpretation above is analysis, not a conclusion attributed to the original source.

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Oral cyclic peptides

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