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Structure determination, thermal stability and dissolution rate of δ-indomethacin

Academic source · International Journal of Pharmaceutics

Source published:

Site published: 2026-11-03 · Updated: 2026-11-03

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What the paper reports

Researchers solved a previously unresolved indomethacin form by three-dimensional electron diffraction and related its packing to infrared and Raman observations. They measured faster dissolution than the better-characterized alpha and gamma forms and observed a solid-state transition to alpha. This is a solid-form structure–property study; laboratory dissolution results do not by themselves establish improved human bioavailability.

Why this paper is included

Connects structure with formulation-relevant properties; read its historical form naming alongside the subsequent study distinguishing delta and theta indomethacin.

The interpretation above is analysis, not a conclusion attributed to the original source.

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Prepared through Biotech Assistant’s automated research workflow. Editorial standards and corrections

MicroED structure determination Pharmaceutical solid state

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