COMPANY RESEARCH

XtalPi

PepiX™ connects AI, automated synthesis, and experimental screening. The website identifies oral cyclic peptides as a priority; food-peptide GRAS status is not pharmaceutical evidence.

Company at a glance

Corporate information

Company entity
晶泰科技(Hong Kong-listed XtalPi group)
Headquarters / principal office
Somerville, MassachusettsSelf-reported location on the company LinkedIn page; regional scope may differ from the legal or global headquarters. ↗
Founded
2015 ↗
Ownership / capital status
Publicly tradedPublicly traded (HKEX 2228, 2024) ↗
Official corporate reference
https://www.xtalpi.com/ ↗
LinkedIn company page
LinkedIn ↗ ↗
Latest financing / award identified
2026-01-28 · Zero-coupon convertible bonds · HKD 2.866 billion principal ↗

Convertible bond principal; neither IPO net proceeds nor the 2025 placement amount.

Profile review: 2026-11-04 · Fields retain their individual source dates. Undisclosed values are not zero; early or historical events do not establish the latest financing. Awards and acquisitions are distinguished from equity rounds.

Public financial snapshot

Amounts retain their original currency and units. Consolidated group revenue is not standalone CRO/CDMO service revenue. Year-to-date periods are not standalone quarters.

PeriodCurrency / basisRevenueNet profitOperating cash flowReport
FY2025
2025-12-31
CNY
IFRS / consolidated
802,623,000123,747,000
Net income attributable to owners of the parent
-165,411,000Original ↗
2026H1
2026-06-30
CNY
IFRS / consolidated
393,627,000-251,901,000
Net income attributable to owners of the parent
-399,238,000Original ↗
FY2025 · Reporting notes
  • Consolidated group figures include proprietary products and other businesses and are not equivalent to the CRO/CDMO segment.
  • Adjusted earnings represent non-IFRS group net income/(loss), not the PRC parent-attributable measure excluding nonrecurring items, and must not be mixed with reported parent-attributable earnings.
  • Parent-attributable results moved to profit from a loss in 2024; fair value changes and other income affect group earnings.
  • publishedAt is the annual results announcement date. reportUrl links to the subsequently issued full annual report; its actual publication date was not individually verified.
2026H1 · Reporting notes
  • Consolidated group figures include proprietary products and other businesses and are not equivalent to the CRO/CDMO segment.
  • Adjusted earnings represent non-IFRS group net income/(loss), not the PRC parent-attributable measure excluding nonrecurring items, and must not be mixed with reported parent-attributable earnings.
  • Parent-attributable results moved from prior-period profit to loss. Total revenue retains the reported -23.9% year-over-year change, rather than the 73.8% figure excluding one-time items.
  • publishedAt is the interim results announcement date. reportUrl links to the full interim report; its actual publication date was not individually verified.

Disease tags match recorded text mentions and require program-level verification.

Technology, programs & evidence

PepiX™ connects AI, automated synthesis, and experimental screening. The website identifies oral cyclic peptides as a priority; food-peptide GRAS status is not pharmaceutical evidence.

The solid-state platform combines prediction and experiments and offers a dedicated crystal structure determination service.

The structure determination page lists small-molecule drugs, salts, cocrystals, mixtures, and structural isomers and discloses a Glacios 200 kV platform.

XtalGazer uses prediction and experiments for solid-form selection. Experimental and computational evidence must be distinguished for each project.

Original 2025 and 2026 interim earnings announcements disclose drug-discovery solutions revenue and group results.

Listed entity HKEX 2228; financials are consolidated group figures.

Program / serviceTarget / indicationRepresentative stageEvidence & scope
PepiX™ oral cyclic peptide researchNot disclosed · Not disclosed未披露Quantitative human results not confirmed in this review
Solid-state R&D capabilitiesDetermined by the submitted sample and research question · Not applicable; service capabilityServices / platformNot applicable; not a human clinical program
MicroED / 3D ED service capabilitiesDetermined by the submitted sample and research question · Not applicable; service capabilityServices / platformNot applicable; not a human clinical program
AI drug discovery and laboratory servicesClient-specific projects · Client-specific projectsServices / platformService capability does not represent clinical evidence for a proprietary candidate

Related news & literature

Company-name matches are discovery leads; verify entity identity and transaction roles in the original source.

No cataloged update explicitly mentions this company.

Same-field reading (not company-specific)
Biotech Assistant · Original commentary · Blog / commentary

How MicroED is Transforming Drug Polymorph Research Workflow

This article explores how Microcrystal Electron Diffraction (MicroED) is set to revolutionize drug polymorph research workflows. Drawing upon recent news, official websites, and LinkedIn updates from Crystal Pharmatech and Eldico, it clearly distinguishes between verified facts, industry viewpoints, and information pending verification.

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Sources & open questions

  • Public information reviewed is insufficient to reconstruct the complete formulation, absolute bioavailability, variability, or food effects.
  • Public sources confirm service availability. Sample suitability, scope of work, pricing, turnaround time, success criteria, and the quality system require direct confirmation.
  • This record describes service capabilities, not the clinical progress of a drug candidate or an independent validation of service success rates.
  • Website throughput and speed figures are company-reported and do not guarantee success rates or delivery times for all samples.
  • MicroED refinement, the scope of CSP support, report quality, raw data, and the execution site require confirmation in the scope of work.
  • The group does not separately disclose all CRO/CDMO profit on a directly comparable basis; group valuation or profit should not directly determine assessments of this business.
  1. PepiX™ AI + 实验Oral Cyclic Peptides方向 ↗XtalPi / 晶泰科技 · Undated
  2. XtalGazer ↗XtalPi · Undated; retrieved 2026-11-01
  3. Crystal Structure Determination ↗XtalPi · Undated; retrieved 2026-11-01
  4. 晶泰控股 2025年年度报告/年度业绩公告 ↗晶泰控股 · 2026-03-25
  5. 晶泰控股 2026中期报告/业绩公告 ↗晶泰控股 · 2026-08-19
  6. About XtalPi / history ↗XtalPi · Not stated
  7. XtalPi company page ↗XtalPi · Not stated
  8. XtalPi HKEX debut ↗XtalPi · 2024-06-13
  9. XtalPi issuer announcement: completion zero coupon bonds ↗XtalPi / HKEX · 2026-01-28
  10. 晶泰科技 | 人工智能 × 机器人Technology Platform赋能行业创新 ↗XtalPi ·
  11. XtalPi 2025 Annual Report (full annual report) ↗XtalPi · Not dated
  12. XtalPi 2026 Interim Report (full interim report) ↗XtalPi · Not dated

Inclusion is not endorsement or partner qualification. Assess company claims, clinical evidence, and project-specific capabilities separately.

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