临床药理与模型引导开发
…rmacology and modeling around exposure, response, and dose decisions. PopPK PK / PD Exposure–response PBPK / QSP 剂量选择依赖哪些证据和假设？ Which evidence and assumptions support dose selection? 如何评价暴露与反应分析中的不确定性？ How should uncertainty in exposure–response analyses be assessed? 何时需要群体PK、PBPK或QSP方法？ When should…
临床药理与模型引导开发